International Journal of Multidisciplinary Health Sciences and Research

Category: Review Article,      DOI: Recived: 29/04/2024, Accepted: 26/05/2024, Published online: 16/06/2024

Emerging medical properties of Calotropis gigantea – A Review

Aman Rehan 1, Aastha Sharma 2*

Abstract:

Calotropis gigantea, commonly known as giant milkweed or crown flower, is a ubiquitous weed that thrives along roadsides throughout the Indian subcontinent, encompassing the geographical regions of India, Pakistan, and Bangladesh. This plant has been an integral part of traditional medicine systems for centuries, demonstrating remarkable therapeutic potential through its antimicrobial, antioxidant, and anti-inflammatory properties across various health conditions. In the face of the growing global challenge of antimicrobial resistance (AMR), the demand for novel, naturally derived compounds has increased exponentially. This urgent need has sparked renewed interest in plants like C. gigantea as potential sources of new antimicrobial agents. This comprehensive review aims to collate and analyze the findings from numerous studies conducted on C. gigantea, focusing on four key areas of research: antimicrobial activity, antioxidant properties, toxicity profile, and wound healing capabilities. By examining the plant's efficacy against various pathogens, its capacity to neutralize harmful free radicals, assessing the safety and potential side effects of its derived compounds, and exploring its potential in promoting tissue repair and regeneration, this review seeks to provide a holistic understanding of C. gigantea's pharmacological properties. Through this synthesis of available scientific evidence, the review aims to elucidate C. gigantea's potential applications in modern medicine, particularly in addressing the pressing issue of AMR and developing novel therapeutic strategies.